PGA
Synthetic absorbable surgical suture PGA is used for closing and suturing of soft tissues, also in ophthalmological interventions. Not suitable for cardiovascular and neurological
interventions. After implantation of the synthetic absorbable surgical suture PGA, moderately severe local inflammation of the tissue is observed, a characteristic reaction to a foreign body, followed by phased transformation into fibrous connective tissue. There follows a partial loss of endurance and suture volume due to their absorption through mechanical hydrolysis during which the polymer is broken down into glycolic acid which is absorbed and passed through body-to-body metabolism. During the absorption of the suture PGA first notices a loss of endurance, without significant loss of mass. The PGA suture has a tensile strength of over 75% of the European Pharmacy requirements at the end of the second week after its implantation and over 35% at about the end of the third week. Suture absorption is complete within 50-90 days.
NEOSORB (PGLA)
Polyglactin sutures are intended for soft tissue attachment or closure, including use in ophthalmic procedures, but its use is not intended for
the tissues of the central cardiovascular and central nervous system. After its implantation, the synthetic absorbable surgical suture NEOSORB PGLA causes a very low level of tissue inflammation, which is followed by a corresponding local formation of fibrous connective tissue. The NEOSORB PGLA suture material is detached by hydrolysis processes, during which the copolymer is broken down into glycolic and lactic acid, and due to the gradual loss of strength, it is finally resorbed by the tissues. The suture material NEOSORB PGLA has a residual strength of 50% after 3 weeks. The suture material is absorbed within 56-70 days.
NEOSORB RAPID (PGLA)
The NEOSORB-PGLA RAPID synthetic absorbable surgical suture is intended for the attachment or closure of soft tissues,
including use in oral mucosa, plastic surgery and generally where short term support is needed. Its use is not indicated for the tissues of the central cardiovascular, central nervous and visual systems. After its implantation, the synthetic absorbable surgical suture RAPID PGLA (RPGLA) causes a very low level of tissue inflammation, which is followed by a corresponding local formation of fibrous connective tissue. The RAPID PGLA(RPGLA) suture material is detached by hydrolysis processes, during which the copolymer is degraded into glycolic and lactic acid, and due to the gradual loss of strength, it is finally resorbed by the tissues. The suture material RAPID PGLA (RPGLA) has a residual strength of 50% after 5 days. The suture's full initial strength occurs within 10-14 days after implantation. The suture material is absorbed within 42 days
MONOFAST
The MONOFAST surgical suture is suitable for suturing soft tissues, with the exception of cardiovascular tissue and the CNS.
In addition, it cannot be used for ophthalmological and microsurgical interventions. The implantation of the synthetic absorbable surgical suture MONOFAST first causes an inflammatory reaction in the tissue, similar to that to a foreign body, and then local connective tissue is formed. There follows a gradual loss of endurance and suture volume due to absorption by hydrolysis, in which the suture is broken down into adipic acid and eventually completely absorbed and degraded by tissue. When the suture is absorbed, a loss of endurance is observed first, without a significant decrease in volume. The suture maintains a remaining endurance of 68-78% after one week and up to 30% towards the end of the second week. Suture absorption is complete after a period of 90 to 110 days. The sum of the initial endurance is lost after about 28 days.
MONOSORB
even used in microsurgical and ophthalmological interventions. Use is not indicated for tissues of the cardiovascular system and CNS. The implantation of the synthetic absorbable surgical suture MONOSORB first causes an inflammatory reaction in the tissue, similar to that to a foreign body, and then local connective tissue is formed. There follows a gradual loss of endurance and suture volume due to absorption by hydrolysis, in which the suture is broken down into carbon dioxide and water and completely absorbed by the tissue. During the first stages of absorption, one observes a gradual loss of suture endurance without a corresponding loss of its volume. The MONOSORB suture has an endurance of 65-70% after 4 weeks and 50-60% after 6 weeks. Suture absorption is completed after a period of 180 to 220 days after implantation.
Synthetic surgical suture MONOSORB is used for general approximation of soft tissues,